The body's accumulation of uric acid is the main cause of gout. Purines, which are chemicals present in some diets and that the body also produces, are broken down by the body to form uric acid, a natural waste product. The body normally excretes uric acid through the urine after it dissolves in the blood. But in those who have gout, the body either creates too much uric acid or is unable to get rid of it properly, which causes it to build up and cause urate crystals to form in the joints.

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